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AggRecetin 10-15mg Ristocetin

Catalog No.:        100970

Net Contents:      1 x 15.0 mg  AggRecetin (Ristocetin)

                            1 x   2.0 mL Diluent

AGGRECETIN® 10 - 15mg   Ristocetin

AggRecetin®: Revealing Platelet Function through Ristocetin Cofactor Activity Testing

AggRecetin® (Ristocetin) is the required reagent, used in combination with other IVD components, to perform a Ristocetin Cofactor Activity test on Platelet Rich Plasma

  • Mediates Platelet Adhesion (Agglutination) by Binding to Collagen and Platelets

  • Causes vWF to Bind to the Gp1B Platelet Receptor

  • Used with Patient Platelet Poor Plasma and Fixed Platelets to Perform the Ristocetin Cofactor Activity Assay

  • Determines the Presence and Integrity of the Platelet Glycoprotein (GP) Ibα-V-IX Complex and von Willebrand Factor (VWF) Interaction when Performed Using Platelet Rich Plasma

  • Causes Ristocetin Induced Platelet Aggregation (RIPA) in Platelet Rich Plasma Samples when AggRecetin is Added in Two Concentrations

PRODUCT DETAILS

AggRecetin® (Ristocetin) emerges as a lyophilized manifestation of Ristocetin A Sulfate, a compound with an enigmatic chemical structure extracted from Nocardia lurida. The composition of AggRecetin is particularly noteworthy, containing an impressive concentration of over 90% Ristocetin A, thereby affirming its status as a substance of exceptional purity and potency.

The functionality of AggRecetin (Ristocetin) within the complex orchestration of platelet dynamics is equally remarkable. In the intricate interplay between Ristocetin and the von Willebrand factor, a captivating phenomenon unfolds. This substance has the unique ability to induce the agglutination of platelets, a process observed in both platelet-rich plasma and standardized fixed platelet suspensions.

Delving into the molecular ballet that occurs in the presence of Ristocetin, it becomes evident that this substance serves as a catalyst, prompting the intriguing interplay between platelets and von Willebrand factor. The agglutination witnessed in platelet-rich plasma or standardized fixed platelet suspensions not only underscores the potency of AggRecetin (Ristocetin) but also offers a nuanced glimpse into the complex mechanisms governing platelet behavior. This revelation holds particular significance in the broader context of hemostasis and coagulation, contributing to our understanding of the intricacies that regulate these vital physiological processes. AggRecetin, with its high concentration of Ristocetin A, thus emerges not merely as a reagent but as a key to unraveling the mysteries of platelet function and the intricate web of interactions that define hemostatic balance.

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Please delve into the literature provided on this page, including the AggRecetin Reagent Product Data Sheet, Routine Agonist Expected Results Chart, and the AggRecetin Instruction for Use (IFU), along with the AggRecetin Safety Data Sheet (SDS) — available in six languages. Furthermore, for our European and United Kingdom customers and distributors, examine the AggRecetin EU Declaration of Conformity and the AggRecetin UK Declaration of Conformity to ensure compliance and understanding tailored specifically for these regions. This information is essential for a thorough understanding of the product details and specifications.

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