PLATELET AGGREGOMETERS
Revolutionize Hematology Testing with Our Advanced Platelet Aggregometers
Bio/Data Corporation offers the state-of-the-art PAP-8E Platelet Aggregometer, incorporating advanced technology. This specialized Light Transmission Aggregometer (LTA) is employed to analyze platelet aggregation by detecting alterations in light transmission through a blood sample. The PAP-8E Platelet Aggregometer serves as a comprehensive diagnostic tool, facilitating both Routine and Special Aggregation Testing, evaluating Ristocetin Cofactor Activity, scrutinizing the effects of Anti-Platelet Drugs, and possessing the capability to identify Heparin-Induced Thrombocytopenia. The PAP-8E Platelet Aggregometer plays a crucial role in the exploration of platelet functionality, the diagnosis of platelet disorders, and the assessment of the impact of antiplatelet medications. When paired with the PDQ Platelet Function Centrifuge and the Picus Pipette, it creates an inseparable trio that significantly elevates the reliability and precision of the results.
Light transmission Platelet Aggregometers are invaluable instruments for investigating platelet function, and they are indispensable in the identification and management of platelet disorders. They operate by continuously monitoring changes in the optical density of a blood sample. As platelets aggregate and form clumps in response to various agonists, the sample becomes increasingly opaque, resulting in a heightened optical density. These aggregometers provide precise and reproducible measurements of platelet aggregation responses to diverse agonists, making them essential tools in both research and clinical laboratory settings.
Platelet aggregometers have the capability to employ a variety of routine agonists to induce platelet aggregation, including ADP (adenosine diphosphate), Arachidonic Acid, Collagen, Epinephrine, and Ristocetin. Different agonists activate specific pathways, enabling researchers to evaluate platelet responsiveness to various physiological and pharmacological cues. The data generated by platelet aggregometers is typically presented graphically in the form of aggregation tracings or curves, illustrating alterations in optical density or impedance over time. Researchers can scrutinize these curves to assess numerous facets of platelet function, such as the lag time to aggregation, the extent of maximal aggregation, and the rate of aggregation.
Platelet Aggregometers find primary application in clinical and research environments to appraise platelet function and diagnose platelet disorders, such as thrombocytopenia and von Willebrand disease. Additionally, they are instrumental in investigating platelet responses to various anti-platelet medications, including Aspirin and Clopidogrel (Plavix®). In various fields, including hematology, cardiology, and pharmaceutical research, optical aggregometers play a vital role. They contribute significantly to the study of platelet disorders, the assessment of anti-platelet treatments, and our understanding of hemostasis and thrombosis.