vW Select - Ristocetin CoFactor Activity Assay System

Catalog No.: 106730

Net Contents: AggRecetin Reagent 2 x 15.0mL

AggRecetin Diluent 2 x 2.0mL

Lyophilized Platelets 2 x 10.0mL

vW Abnormal Control Plasma 5 x 0.5mL

vW Normal Control Plasma 5 x 0.5mL

vW Normal Reference Plasma 5 x 0.5mL

Tris Buffered Saline 3 x 10.0mL

vW SELECTTM
Ristocetin Cofactor Activity Assay System

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vW Select: Revolutionizing von Willebrand Analysis with the Ultimate All-In-One Ristocetin CoFactor Assay Test Kit

vW SelectTM is an All-In-One Ristocetin Cofactor Activity Assay System comprised of reagents, control plasmas, and lot specific technical information optimized to elicit the agglutination of lyophilized platelets in the presence of the patient’s Platelet Poor Plasma and Ristocetin.

Reagents Optimized to more Effectively Perform Ristocetin Cofactor Activity Assay
Offers a Three or Four Point Standard Curve
Achieves Linear Standard Curves
Replaces Lab Developed Tests for Regulatory Compliance
Shows Inflammatory Responses
Provides Lot Specific Reagent Information and Assay Value Sheet
Improves Test Performance, Sensitivity, and Repeatability
Reduces Assay and Laboratory Test Variables
Includes Control and Reference Plasmas
Use with Most Light Transmission Aggregometers
Plasmas Traceable to WHO Standard Reference Plasma
Suitable for Veterinary Use

The vW Select Test Kit represents a groundbreaking advancement in platelet function analysis, offering a comprehensive All-In-One Ristocetin Cofactor Activity Assay System. This system includes meticulously optimized reagents, control plasmas, and lot-specific technical information tailored to induce the agglutination of lyophilized platelets in the presence of the patient's Platelet Poor Plasma and Ristocetin.

Explore Product Data Sheet

The reagents within vW Select are finely tuned for optimal performance in Ristocetin Cofactor Activity Assay, presenting a three or four-point standard curve that achieves linearity. This innovative system replaces traditional lab-developed tests, ensuring regulatory compliance. Additionally, it reveals inflammatory responses, providing valuable insights into the patient's condition. The comprehensive package includes lot-specific reagent information and an assay value sheet, enhancing test performance, sensitivity, and repeatability while reducing assay and laboratory test variables.

Ristocetin Cofactor, as measured by the in-vitro activity of von Willebrand factor, triggers platelet agglutination. Reduced von Willebrand factor is associated with von Willebrand Disease, making quantitation of ristocetin cofactor activity crucial for diagnosis and evaluation of this coagulopathy. The assay is also instrumental in monitoring patient response to therapy. Results are determined by the ability of a test plasma and ristocetin to induce agglutination of a standardized platelet suspension, with outcomes interpreted using a lot-specific Standard Reference Curve.

The vW Select 50 Determination Complete Test Kit further simplifies the process, including lyophilized platelets, AggRecetin Reagent (Ristocetin), vW Normal Reference Plasma, vW Abnormal Control Plasma, vW Normal Control Plasma, Tris Buffered Saline, and AggRecetin (Ristocetin) Diluent. This comprehensive kit provides the necessary components for a thorough platelet function analysis, ensuring accuracy and reliability in clinical diagnostics.

Take a detailed look at the information provided here, specifically the vW Select Product Data Sheet. Also, review the vW Select Instruction for Use (IFU) and the vW Select Safety Data Sheet (SDS), both offered in six languages. For our customers and distributors in Europe and the United Kingdom, conduct a meticulous examination of the vW Select EU Declaration of Conformity and the vW Select UK Declaration of Conformity to ensure compliance and a tailored understanding. To gain a comprehensive understanding of the product's specifications and details, it is imperative to review this information.

Bio/Data Corporation’s Aggregation Reagents: Accessible Safety Data Sheets for Secure Handling

Bio/Data Corporation provides comprehensive Safety Data Sheets (SDS) for each of its carefully formulated aggregation reagents. These essential documents ensure safe handling, storage, and spill management while offering clear instructions on potential hazards. Designed for easy viewing, saving, and printing, the SDS are readily accessible to support a safe work environment and responsible chemical management.

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Product Description

vW Select is a Ristocetin Cofactor Assay System comprised of optimized reagents, control plasmas and lot specific technical information for use in the detection of von Willebrand Disease (vWD). The materials provided in the vW Select system have been specifically selected to provide improved performance and repeatability compared to ordinary component combinations found in existing Ristocetin Cofactor assay systems.

Review Instructions For Use

Intended Purpose

The vW Select Ristocetin Cofactor Assay System is optimized to elicit the agglutination of lyophilized platelets in the presence of the patient’s Platelet Poor Plasma and Ristocetin.

Test Principle

Ristocetin Cofactor is the in-vitro activity of the von Willebrand factor which causes the agglutination of platelets in the presence of Ristocetin. Decreased von Willebrand factor is associated with von Willebrand Disease, The quantitation of Ristocetin cofactor activity is useful in the diagnosis and evaluation of this coagulopathy. It is also useful when monitoring patient response to therapy. Levels of Ristocetin cofactor activity are determined by the ability of a test plasma and Ristocetin to induce agglutination of a standardized platelet suspension. Results are determined using a lot specific Standard Reference Curve.

READ MORE... Easily Download the vW Select Test Kit Instructions for Use in Your Selected Language.

Reagents Provided

AggRecetin Reagent, 2 x 15.0mL.

AggRecetin Diluent, 2 x 2.0mL.

Lyophilized Platelets, 2 x 10.0mL.

vW Abnormal Control Plasma, 5 x 0.5mL.

vW Normal Control Plasma, 5 x 0.5mL.

vW Normal Reference Plasma, 5 x 0.5mL.

Tris Buffered Saline, 3 x 10.0mL.

Reagents and Materials Required but Not Provided

Purified Water (Distilled, Deionized, Reagent Grade), pH 5.3 – 7.2 for reconstitution

Materials and Accessories

Platelet Aggregometer
Centrifuge
Electronic Pipette
Pipette Tips
Aggregometer Test Tubes (Siliconized)
Aggregometer Stir Bars (Plastic Coated)
Plastic Sample Tubes and Caps (For Dilutions)

Reagent Storage

Upon receipt, store AggRecetin Reagent, AggRecetin Diluent, Lyophilized Platelets, vW Abnormal Control Plasma, vW Normal Control Plasma, vW Normal Reference Plasma, and TRIS Buffered Saline at 2 – 8° C in its original packaging.
Reconstituted AggRecetin Reagent is stable for 7 days when stored in its’ tightly capped, original container at 2 – 8° C.
Reconstituted Lyophilized Platelets is stable for 30 days when stored in its’ tightly capped, original container at 2 – 8° C.
Reconstituted vW Abnormal Reference Plasma, vW Normal Control Plasma, and vW Normal Reference Plasma is stable for 8 hours when stored in its’ tightly capped, original container at 2 – 8° C.
Dilutions using vW Abnormal Control Plasma, vW Normal Control Plasma, or vW Normal Reference Plasma are less stable and must be used within 40 minutes of preparation.

Bio/Data Corporation's Commitment to IVDR Compliance
Bio/Data Corporation proudly complies with the stringent EU In Vitro Diagnostic Regulation (IVDR) 2017/746 and other relevant legislation. Through its Declaration of Conformity (DOC), the company ensures that its devices meet essential health, safety, and environmental standards.

Bio/Data Corporation's Commitment to UKCA Compliance
Bio/Data Corporation ensures product excellence by strictly adhering to UKCA regulations. The company's Declaration of Conformity (DOC) affirms its dedication to meeting health, safety, and environmental standards outlined in UKCA directives and any related updates, demonstrating its unwavering commitment to compliance.

View EU Declaration of Conformity