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COAGULATION REAGENTS

Innovative Coagulation Reagents Redefine Precision in Hemostasis Testing

Bio/Data Corporation is a leading provider of high-quality coagulation reagents, offering a range of products designed to meet the diverse needs of clinical laboratories engaged in coagulation studies. With a commitment to precision, reliability, and innovation, Bio/Data has established itself as a trusted partner for healthcare professionals seeking advanced solutions in the field of hemostasis testing. The company's coagulation reagents play a pivotal role in diagnosing and monitoring various clotting disorders, providing essential tools for assessing the intricacies of the clotting cascade.

Calcium Chloride
Solution
Calcium Chloride Solution

Catalog # 100989

Sodium Citrate 
Sodium Citrate

Catalog # 100994

Cephalinex®
Cephalinex Reagent

Catalog # 101162

Lupus Anticoagulant Confirmation Reagent™
Lupus Anticoagulant Coagulation Reagent

Catalog # 102516

Plastinex®
Plastinex Reagent

Catalog # 101158

DUE TO SUPPLY CHAIN SHORTAGES, VIAL COLORS MAY VARY

Coagulation reagents play a pivotal role in diagnostic laboratories by facilitating the analysis of blood clotting processes, a critical aspect of hemostasis. These reagents are instrumental in conducting various coagulation tests that provide valuable insights into a patient's clotting profile, aiding in the diagnosis and monitoring of bleeding disorders, thrombotic conditions, and assessing the efficacy of anticoagulant therapies.

One essential coagulation reagent is the Calcium Chloride Solution, boasting a concentration of 0.025 M. This versatile solution is designed to work in tandem with other in vitro diagnostic (IVD) reagents, ensuring accurate and reliable results in coagulation and laboratory tests. Its optimized concentration is particularly tailored for hemostasis testing procedures, making it compatible with a range of analyzers featuring different detection systems, including optical, opto-mechanical, and mechanical technologies.

In the realm of activated partial thromboplastin time (APTT) monitoring, Cephalinex® stands out as a lyophilized preparation of rabbit brain cephalin and microsilica activator. This reagent plays a crucial role in supplying platelet phospholipid substitutes and creating a negatively charged surface necessary for plasma coagulation via the intrinsic hemostatic pathway. By facilitating APTT tests, monitoring heparin anticoagulation therapy, and screening for coagulation factor deficiencies, Cephalinex® contributes to a comprehensive evaluation of the clotting cascade.

For confirming the presence of lupus anticoagulant, the Lupus Anticoagulant Confirmation Reagent™ (LACR) provides precision and compliance with International Society on Thrombosis and Hemostasis (ISTH) guidelines. This platelet extract reagent serves as a vital component in the platelet neutralization procedure, confirming that previous laboratory results correctly identified a sample as containing the lupus anticoagulant. By adhering to ISTH guidelines and supplying additional phospholipids to patient samples and control plasma, LACR ensures accurate confirmatory testing.

Plastinex®, categorized as a thromboplastin, redefines coagulation testing for prothrombin time (PT) and comprehensive factor assays. With a lyophilized formulation that includes rabbit brain thromboplastin, calcium salt, buffers, and stabilizers, Plastinex® ensures standardized and reliable results. By incorporating the International Sensitivity Index (ISI) of the reagent, it allows for the precise assessment of PT, evaluation of multiple coagulation factors, and monitoring of oral coagulation therapy.

Sodium Citrate, with a concentration of 0.11M, emerges as a versatile anticoagulant employed for precise hemostasis testing across both human and non-human species. This reagent is routinely used to anticoagulate whole blood specimens, catering to the diverse requirements of hemostasis testing. Endorsed by the International Society on Thrombosis and Hemostasis (ISTH), Sodium Citrate is packaged to accommodate various anticoagulant volumes, making it a reliable choice for laboratories conducting coagulation studies in different settings and species.

At Bio/Data, a dedication to excellence is reflected in each coagulation reagent, ensuring that laboratories can rely on accurate and consistent results. Whether it's Calcium Chloride Solutions optimized for hemostasis testing procedures, lyophilized Cephalinex® for APTT monitoring, Lupus Anticoagulant Confirmation Reagent™ (LACR) for precise validation of lab results, Plastinex® for redefining coagulation testing, or Sodium Citrate as a versatile anticoagulant, Bio/Data's portfolio is crafted to meet the highest standards of performance and compliance.

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