UPTT™ REAGENT
Non-Activated Partial Thromboplastin Time Reagent

UPTT™ Reagent: Elevating Hemocompatibility Testing Standards of Devices and Materials.

UPTT™ Reagent is a Standardized Reagents for Testing the Hemocompatibility of Devices and Materials.

Lyophilized Preparation of Buffered Rabbit Brain Cephalin
Standardized Phospholipid Concentration
Performing (Non-Activated) Partial Thromboplastin Time (PTT) Tests
Detects Activating Effects of a Device or Extract on the Intrinsic Coagulation Pathway

Catalog No.: 105997

Net Contents: 20 x 3.0 mL

UPTT™ Reagent stands as a pinnacle in standardized reagents designed for meticulously testing the hemocompatibility of various devices and materials. This innovative solution offers a comprehensive approach to evaluating the impact of medical and vascular devices on blood coagulation, specifically honing in on the intrinsic coagulation pathway.

Explore Product Data Sheet

One of the distinguishing features of UPTT™ Reagent lies in its lyophilized preparation of buffered rabbit brain cephalin, ensuring consistency and reliability in each assessment. The inclusion of a standardized phospholipid concentration further enhances the precision of the testing process. When performing (non-activated) partial thromboplastin time (PTT) tests, UPTT™ Reagent provides a robust platform for detecting the activating effects of a device or extract on the intrinsic coagulation pathway.

The significance of biocompatibility, measuring the impact of devices and materials on living organisms, cannot be overstated when considering the suitability of medical or vascular devices for in-vivo applications. UPTT™ Reagent, with its ability to assess both human and animal specimens, emerges as a crucial tool in ensuring the safety and efficacy of these vital healthcare components. Its development underscores a commitment to advancing hemocompatibility testing methods, offering a reliable means of evaluating the intricate interplay between medical devices and the coagulation processes within the body.

Delve into the documentation provided on this page, covering the UPTT™ Reagent Product Data Sheet. Additionally, inspect the UPTT™ Reagent Instruction for Use (IFU) and the UPTT™ Reagent Safety Data Sheet (SDS), both accessible in six languages. It is crucial to scrutinize this information carefully to acquire a comprehensive understanding of the product's specifications and details.

Bio/Data Corporation’s Aggregation Reagents: Accessible Safety Data Sheets for Secure Handling

Bio/Data Corporation provides comprehensive Safety Data Sheets (SDS) for each of its carefully formulated aggregation reagents. These essential documents ensure safe handling, storage, and spill management while offering clear instructions on potential hazards. Designed for easy viewing, saving, and printing, the SDS are readily accessible to support a safe work environment and responsible chemical management.

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Product Description

UPTT Reagent is a lyophilized preparation of buffered rabbit brain cephalin that has a standardized phospholipid concentration of ≤ 0.1%. The UPTT Reagent does not contain activating compounds.

Review Instructions For Use

Intended Purpose

UPTT Reagent is intended for use in performing (non-activated) in-vitro Partial Thromboplastin Time (PTT) tests. This test detects the activating effects of a device or extract on the intrinsic coagulation pathway in platelet poor or platelet free plasma or the deficiency of certain plasma coagulation factors

Principle

Contact activation occurs in the absence of Ca++ following whole blood exposure to a foreign material. The UPTT measures the plasma factors which are involved in the generation of plasma thromboplastin via the intrinsic pathway by detecting the time to clot formation. The test should be run in triplicate. Compare the results following exposure to the test device to those on the untreated plasma and negative controls.

READ MORE... Easily Download the UPTT Reagent Instructions for Use in Your Selected Language.

Reagents Provided

UPTT Reagent, 20 x 3.0 mg.

Reagents and Materials Required but Not Provided

Calcium Chloride, 0.025 M
Sodium Citrate, 0.11M
Coagulation Control Plasma
Purified Water (Distilled, Deionized, Reagent Grade), pH 5.3 – 7.2 for reconstitution
TRIS Buffered Saline (TBS) or 0.85% physiologic saline for dilutions

NOTE: USING BLOOD BANK SALINE WILL CAUSE ERRONEOUS RESULTS.

Materials and Accessories

Platelet Aggregometer
Centrifuge
Electronic Pipette
Pipette Tips
Aggregometer Test Tubes (Siliconized)
Aggregometer Stir Bars (Plastic Coated)
Plastic Sample Tubes and Caps (For Dilutions)

Reagent Storage

Upon receipt, store UPTT Reagent at 2 - 8° C in its original packaging.
Reconstituted UPTT Reagent is stable for 7 days when stored in its’ tightly capped, original container at 2 - 8° C.

Bio/Data Corporation's Commitment to IVDR Compliance
Bio/Data Corporation proudly complies with the stringent EU In Vitro Diagnostic Regulation (IVDR) 2017/746 and other relevant legislation. Through its Declaration of Conformity (DOC), the company ensures that its devices meet essential health, safety, and environmental standards.

Bio/Data Corporation's Commitment to UKCA Compliance
Bio/Data Corporation ensures product excellence by strictly adhering to UKCA regulations. The company's Declaration of Conformity (DOC) affirms its dedication to meeting health, safety, and environmental standards outlined in UKCA directives and any related updates, demonstrating its unwavering commitment to compliance.

View EU Declaration of Conformity

View UK Declaration of Conformity

UPTT™ REAGENT Non-Activated Partial Thromboplastin Time Reagent

UPTT™ Reagent: Elevating Hemocompatibility Testing Standards of Devices and Materials.

UPTT™ Reagent is a Standardized Reagents for Testing the Hemocompatibility of Devices and Materials.

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Lyophilized Preparation of Buffered Rabbit Brain Cephalin

Standardized Phospholipid Concentration

Performing (Non-Activated) Partial Thromboplastin Time (PTT) Tests

Detects Activating Effects of a Device or Extract on the Intrinsic Coagulation Pathway

UPTT™ REAGENT
Non-Activated Partial Thromboplastin Time Reagent