Catalog No.: 106956
Net Contents: 1 x 5.0 mL
TRAP-6 AMIDE Thrombin Receptor Activating Peptide
Unlocking Platelet Behavior: TRAP-6 Amide Reveals Insights into Pro-Coagulant Activity and Thrombin-Initiated Aggregation in Sticky Platelet Syndrome
TRAP-6 amide is a synthetic PAR 1 Antagonist (Thrombin Receptor Activating Peptide). This peptide fragment irreversibly stimulates platelets to aggregate, undergo structural changes, and to degranulate.
Investigate Platelet Dependent Pro-Coagulant Activity
Assess Thrombin Initiated Platelet Aggregation
Confirm Platelet Function & Reactivity In The Presence Of Thienopyridines
Study Sticky Platelet Syndrome
TRAP-6 amide, an engineered Thrombin Receptor Activating Peptide (PAR 1 Antagonist), emerges as a potent agent capable of instigating irreversible responses within platelets. This synthetic peptide fragment not only induces the aggregation of platelets but also triggers significant structural alterations and the initiation of degranulation processes.
Our investigative journey encompasses a multifaceted approach, each facet contributing to a more nuanced comprehension of TRAP-6 amide's impact. The primary objective is to unravel the intricacies of Platelet Dependent Pro-Coagulant Activity, shedding light on the mechanisms through which platelets contribute to the coagulation process. Simultaneously, we delve into the dynamics of Thrombin Initiated Platelet Aggregation, dissecting the molecular intricacies governing this critical phase of platelet response.
In addition, we embark on a quest to Confirm Platelet Function and Reactivity in the Presence of Thienopyridines, exploring how the interplay between TRAP-6 amide and these compounds influences platelet behavior. This comprehensive exploration extends its reach to the enigmatic domain of Sticky Platelet Syndrome, seeking to unveil the underlying factors and mechanisms contributing to this intriguing phenomenon.
Within the context of these investigations, when introduced to normal Platelet Rich Plasma or select platelet preparations, the TRAP-6 reagent consistently evokes a robust, concentration-dependent monophasic response. This observed reaction serves as a dynamic window into the complex interplay between TRAP-6 amide and platelet dynamics, providing a rich tapestry of information for furthering our understanding of the intricate relationships at play in hemostasis and platelet functionality.
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