Catalog No.: 102516
Net Contents: 5 x 1.0 mL
LUPUS ANTICOAGULANT CONFIRMATION
REAGENT™ (LACR) Platelet Extract Reagent
Lupus Anticoagulant Confirmation Reagent™: Validating Lab Results with Precision and ISTH Compliance
Lupus Anticoagulant Confirmation Reagent™ is a platelet phospholipid solution used to perform the platelet neutralization procedure. Use of the LA-CR test kit confirms that previous laboratory results have correctly flagged a sample as containing the lupus anticoagulant.
Optimized Source of Human Phosphatidyl Platelet Phospholipids
Used to Perform Platelet Neutralization Procedure (PNP) Needed as Part of a Multi-Test Investigation for the Presence of the Lupus Anticoagulant
Meets ISTH Guidelines for Confirmatory Testing by Providing Additional
Phospholipids to Patient Sample and Control Plasma
Lupus Anticoagulant Confirmation Reagent™ serves as a crucial platelet phospholipid solution designed for the execution of the platelet neutralization procedure (PNP). This innovative LA-CR test kit plays a pivotal role in confirming the accuracy of previous laboratory results, specifically identifying samples that contain the lupus anticoagulant.
Functioning as an optimized source of human phosphatidyl platelet phospholipids, this reagent is integral for conducting the Platelet Neutralization Procedure (PNP). This procedure is a vital component of a comprehensive multi-test investigation aimed at detecting the presence of the lupus anticoagulant in patient samples. Adhering to the guidelines set forth by the International Society on Thrombosis and Haemostasis (ISTH), our test kit ensures confirmatory testing by providing additional phospholipids to both patient samples and control plasma.
In cases where an undetermined prolonged activated partial thromboplastin time (APTT) is observed, the likely culprit is the presence of the lupus anticoagulant in the plasma. The inhibitory activity of this anticoagulant is often evident in phospholipid-dependent coagulation reactions, with a higher frequency in APTT compared to Prothrombin Time (PT). The introduction of Lupus Anticoagulant Confirmation Reagent effectively shortens the APTT time that is prolonged in the presence of the lupus anticoagulant. Consequently, the platelet neutralization procedure emerges as a valuable diagnostic test, enabling the differentiation of lupus anticoagulant from specific factor inhibitors, such as Factor VIII inhibitor.
With a net contents of 5 x 1.0 mL, our Lupus Anticoagulant Confirmation Reagent™ stands as an indispensable tool in enhancing the precision and reliability of lupus anticoagulant detection, contributing to more accurate and efficient diagnostic practices in the realm of coagulation studies.