Catalog No.: 106075 (USA & Canada)

Catalog No.: 106077 (Export)

PAP-8E PLATELET AGGREGOMETER

Experience Unmatched Accuracy in Hemostasis Testing with the PAP-8E Platelet Aggregometer

The PAP-8E is an advanced Platelet Aggregometer for Clinical, Reference, and Research Laboratory applications. Exceptional ease of use and standardized test procedures allow for rapid, routine testing for platelet function. Comprehensive results include area under the curve, area under the slope, and user defined analyses.

Eight Independently Operated Test Channels
Nine Test Results Reported per Channel
Standard Micro-Volume (225 µL) Samples
User Defined Test Templates & Protocols
Walk-Away Operation

Net Contents:

PAP-8E Platelet Aggregometer, All-In-One Wireless Computer, PAP-8E System Software, Picus® 2 Electronic Pipette, Microsoft® Office Suite, and Color Printer (USA & Canada)

The PAP-8E Platelet Aggregometer stands as a cutting-edge aggregation instrument tailored for a spectrum of applications, spanning Clinical, Reference, and Research Laboratory settings. Renowned for its exceptional user-friendliness and adherence to standardized test procedures, this advanced aggregometer ensures swift and routine testing for platelet function, providing comprehensive results that encompass the area under the curve, area under the slope, and customizable user-defined analyses.

What sets the PAP-8E apart is its ability to efficiently function across eight independently operated test channels, delivering nine test results per channel. The utilization of standard micro-volume (225uL) samples enhances practicality and resource efficiency. Users have the flexibility to define test templates and protocols, contributing to a versatile testing environment. The system's walk-away operation further streamlines processes, allowing for seamless integration into laboratory workflows.

The PAP-8E Platelet Aggregometer serves as a complete test system, encompassing essential components such as the aggregometer itself, an All-In-One Wireless Computer, PAP-8E System Software, a Programmable Picus® 2 Electronic Pipette, Microsoft® Office Suite, and a Color Printer (available in the US and Canada).

Moving beyond its hardware specifications, the PAP-8E emerges as a comprehensive diagnostic tool with diverse applications. It facilitates Routine and Special Aggregation Testing, assesses Ristocetin Cofactor Activity, analyzes the effects of Anti-Platelet Drugs, and detects Heparin-Induced Thrombocytopenia. Tailored specifically to support the identification and diagnosis of hemostasis disorders, both inherited and acquired platelet dysfunctions, this system excels in measuring the speed and extent of activation, aggregation, agglutination, and inhibition reactions.

Explore PAP-8 Product Data Sheet

Explore Software Product Data Sheet

Explore Pipette Product Data Sheet

Operators benefit from on-screen timers and audible alarms, enabling multitasking during incubation and test sequences. The device's efficient use of micro-volume quantities minimizes sample and reagent consumption, contributing to cost-effective and sustainable laboratory practices. Preprogrammed procedure templates triggered by agonists facilitate a variety of tests, ensuring consistent and standardized testing procedures over time.

Seamlessly blending precision, efficiency, and versatility, the PAP-8E Platelet Aggregometer remains at the forefront of Platelet Function technology with its continuous upgrades. This comprehensive instrument, designed for clinical, reference, and research laboratory applications, undergoes perpetual evolution in both software and hardware. From dynamic software enhancements to meticulous hardware improvements and an integrated All-In-One Computer System, the PAP-8E adapts to the evolving landscape, ensuring it stays on par with the latest advancements. This commitment not only preserves its relevance but propels it forward as an agile and responsive diagnostic tool, meeting the diverse demands of modern laboratory environments.

Kindly peruse the literature provided, including the PAP-8E Platelet Aggregometer Product Data Sheet, PAP-8E System Software Product Data Sheet, and Picus Pipette Product Data Sheet. Also, review the PAP-8E's EU Declaration of Conformity and UK Declaration of Conformity for our European and United Kingdom customers and distributors, ensuring compliance and tailored understanding for these regions. This information is vital for a comprehensive understanding of product details and specifications.

SYSTEM COMPONENT INCLUDED

PAP-8E Platelet Aggregometer
All-In-One Wireless Computer
PAP-8E System Software
Programmable Electronic Pipette with Charging Stand
Microsoft® Office Home and Business 2021
Color Printer (USA & Canada)

OPTIONAL ACCESSORIES

PDQ®, Platelet Function Centrifuge
Reagent Well Adapters
Bar Code Reader

PAP-8E Platelet Aggregometer with PDQ Platelet Centrifuge

The PAP-8E Platelet Aggregometer

with the PDQ Platelet Function Centrifuge

TESTING CAPABILITIES

Eight Test Channels

Displays Results from Eight Individual Patient Samples, Eight Separate Agonists, Eight Agonist Concentrations, or Any Combination at the Same Time.

Nine Reported Results

Generates Nine Test Results per Channel: Primary Aggregation, Primary Slope, Secondary Aggregation, Secondary Slope, Area Under The Curve, Lag Phase, Dis-Aggregation, Maximum Aggregation, and Final Aggregation.

User-Defined Test Templates & Protocols

Create, Define, and Store Non-Standard Test Procedures including TRAP-6, U46619, Dilution Curve Profiles, and Platelet Activation.

Ability to Control the Following Parameters:

Temperature Settings: Choose Incubation Block Temperatures from 32° - 45° C.

Timers & Alarms: Set Incubation, Injection, and Test Times for Each Channel.

Stir Speeds: Adjust Test Well Stir Speeds and Reagent Warming; Incubation Well Stir Speeds From 50 - 1200 RPMs.

Test Duration: Select Up to 4 Hours for Each Test Type.

Trace Filter Selection

Turn Curve Smoothing Feature On or Off for Each Test Well In Set-Up or During Any Test.

Compromised Sample Recognition

Ability to Confirm and Document Compromised Samples.

Pre-Loaded Test Templates & Protocols

Automatically Loads Chosen Test Type for:

Routine Testing: Multiple Tests, ADP, Arachidonic Acid, Collagen, Epinephrine, Heparin Induced Platelet Aggregation (HIPA), Ristocetin Induced Platelet Aggregation (RIPA), Thrombin Induced Platelet Aggregation (TIPA) for Platelet Rich Plasma (PRP) or Washed Platelets, Spontaneous Aggregation, Direct Mode and LTA Check.

Special Aggregation Testing: Heparin Induced Thrombocytopenia (HIT), Dose Response Curves, and Sticky Platelets.

Ristocetin Cofactor Activity Assay: Select Three or Four Point Standard Curves. Linearity Check Provided Prior to Accepting Test Results.

Direct Mode: Allows the User Rapid Access to the Analyzer Functions, Bypassing Data Entry Screens and Goes Directly to the Status Screen.

Main Menu

PAP-8E Platelet Aggregometer System Software

Ristocetin Cofactor Assay for Standard 3 Point Curve

Ristocetin Cofactor Three Point Curve Result

Data Analysis of Area Under The Curve

DATA ANALYSIS MANAGEMENT

Data Analysis

Enables User to Analyze Any Portion of the Aggregation Curve (Current, Stored, or Archived Data) without Affecting the Original Data.

User Selected Data Point Analysis

Any Reported Result: Primary Slope, Secondary Slope, Area Under The Curve, Lag Phase, Dis-Aggregation, Shape Change and Area Under the Slope.

Database

Generate Patient Specific Cumulative Reports; Sort Data by Individual Fields; and Archive Multiple Databases.

Control Feature

Allows the User to Select Results from a Known Normal Donor to Include with Each Patient’s Results for Interpretation.

Data Exporting

Select Test Data for Direct Export into Microsoft® Excel or Other Statistical Programs, such as Prism®.

Data Recall Feature

Access Any Test Result or Report at Any Time.

Clip Feature

Copy Test Results and Insert Into Any Microsoft Office Program. Results Can Be Easily Emailed.

OPERATOR SUPPORT

On-Screen Help

On-Screen Access to Operation and Methods Manuals.

On-Demand Optical Calibration Check

Available to Check Instrument Performance and Document Regulatory Compliance.

Event Log

Documents System Performance and Instrument Status.

DATA PROTECTION & SECURITY

Enhanced Password Protection

Operator Specific Passwords, Log-Ins, Time-Outs, Automatic Password Expiration, and Log-In Failure Lock Out, Administrative Level Management Access for Additional Protection.

Secured Database

Accepted Patient Records are Displayed Directly from the Secure CLIA Compliant Database. Comments Can Be Added. All Test Results are Permanently Recorded in a Secured Database.

Convenient Database Archiving, Backup, & Recovery

Archive, Backup or Restore Databases Using a USB Flash Drive or Other Storage Device.

PAP-8E PLATELET AGGREGOMETER

Eight Independently Operated Test Channels
Eight Stirred Activation Wells
Eight Non-Stirred Incubation Wells
Two Reagent Wells
Light Source: UV LED 400–430nm; Automatic Range Adjustment
Blank: 250 µL PPP or PFP
Test Sample: 225 µL PRP
Reagent / Agonist: 25 µL
Temperature Control: 37°C ± 0.5°C
Temperature Range: 32°C - 45°C; User Adjustable
Stirring: Digital: 0 - 1200 RPM Preset for Standard Tests; Operator Controlled for User Defined Tests
Specimens: Human and Veterinary: PRP, PPP, PFP, Washed Platelets, Gel Filtered Platelets, Leukocytes, Red Cells, and AB-AG Solutions
Sensitivity: Agonist Dependent
Results: Nine Test Results Reported Per Channel

COMPUTER

All-In-One 21.5” Touch Screen Wireless Computer
Windows® 11 Professional Operating System
Microsoft® Office Home and Business 2021
PAP-8E System Software

DIMENSIONS

Width: 19.5 inches / 49.53 cm

Depth: 21.7 inches / 55.11 cm

Height: 21.5 - 25.5 inches / 54.61 - 64.77 cm (Adjustable Stand)

Weight: 40.0 pounds / 18.0 kg

ELECTRICAL

Voltage Selector Switch: 120 / 240 VAC, 50 / 60 Hz, 3A Isolated, Grounded Line Required

Effortlessly Perform

Routine and Special Aggregation Testing
Ristocetin Cofactor Activity Analysis
Anti-Platelet Drug Responses
Heparin-Induced Thrombocytopenia Detection

Clinical Laboratory

Measure Ristocetin Cofactor
Confirm HIT (Heparin Induced Thrombocytopenia)
Evaluate and Monitor Patients with Platelet Function Abnormalities
Detect and Monitor Inherited Disease
Manage Anti-Platelet Therapy
Pre and Post-Operative Support of LVAD Patients (Left Ventricular Assist Devices)

Pharmaceutical Laboratory

Study Anti-Platelet Compounds
Examine Anti-Inflammatory or Other Compounds
Microvolume Capacity for Discovery
Pre-Clinical or Small Animal Model Studies

Bio-Technology Laboratory

Measure Activity and Effectiveness of Combination Agents
Study Effects of Engineered Surfaces on Platelet Function
Investigate Dietary Influences on Platelet Function

Research Laboratory

Evaluate Platelet-Vascular Interactions
Examine Anti-Platelet and Lytic Agent Effect in Thrombotic Models or Events

Veterinary Laboratory

Measure Ristocetin Cofactor Activity in Canine and Porcine Species
Study Platelet Function abnormalities in Animals
Measure Platelet Function in Animal Models

Routine Platelet Aggregation

Routine Aggregation Results on PAP-E Platelet Aggregometer

vW Willebrand Factor

Ristocetin Cofactor Three Point Curve Results for PAP-8E Platelet Aggregometer

Special Aggregation

Bio/Data Corporation's Commitment to IVDR Compliance
Bio/Data Corporation proudly complies with the stringent EU In Vitro Diagnostic Regulation (IVDR) 2017/746 and other relevant legislation. Through its Declaration of Conformity (DOC), the company ensures that its devices meet essential health, safety, and environmental standards.

Bio/Data Corporation's Commitment to UKCA Compliance
Bio/Data Corporation ensures product excellence by strictly adhering to UKCA regulations. The company's Declaration of Conformity (DOC) affirms its dedication to meeting health, safety, and environmental standards outlined in UKCA directives and any related updates, demonstrating its unwavering commitment to compliance.

View PAP-8E EU Declaration of Conformity