TX A2, U-46619

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TX A2, U-46619

Platelet response to U-46619 varies with concentration ans species. Monophasic aggregation, biphasic aggregation and disaggregation have been reported in in-vitro test systems.



TX A2 U-46619 is a stable synthetic analog of PGH2, and a specific agonist for the Thromboxane Prostanoid (TP) receptor on the platelet surface. It induces platelet shape change, ativation and aggregation, as well as vascular contraction and platelet accumulation.


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